Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21242136 | 0.80 | CA2 (0.38) | TDP1GRNSORT1SIGMAR1 | |
| SCHEMBL5397395 | 0.80 | KDM4E (0.44) | TDP1GRNSORT1SIGMAR1CPB2 | |
| SCHEMBL30524563 | 0.78 | CA2 (0.37) | TDP1GRNSORT1SIGMAR1 | |
| SCHEMBL2249648 | 0.78 | KMT2A (0.41) | TDP1SLC1A3SLC1A2SLC1A1GGT1 | |
| SCHEMBL31717003 | 0.76 | TDP1 (0.34) | TDP1GRNSORT1SIGMAR1 | |
| SCHEMBL22412993 | 0.74 | NOD1 (0.41) | ACE | |
| SCHEMBL3102110 | 0.73 | CYP2D6 (0.43) | CYP2D6SLC1A3SLC1A2SLC1A1GRN | |
| SCHEMBL4621301 | 0.73 | CYP2D6 (0.43) | CYP2D6SLC1A3SLC1A2SLC1A1GRN | |
| SCHEMBL4620172 | 0.73 | CYP2D6 (0.43) | CYP2D6SLC1A3SLC1A2SLC1A1GRN | |
| SCHEMBL8043159 | 0.72 | TDP1 (0.47) | TDP1CYP2D6TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |