Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833096 | 1.00 | RELA (0.55) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL1795132 | 0.82 | PTGS1 (0.69) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL1795130 | 0.82 | PTGS1 (0.69) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL21847980 | 0.82 | PTGS1 (0.69) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL18378693 | 0.78 | TP53 (0.56) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL23457950 | 0.78 | TP53 (0.60) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL1179749 | 0.78 | RELA (0.74) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL29673932 | 0.78 | RELA (0.74) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL29862171 | 0.78 | TP53 (0.60) | RELATP53TDP1PTGS1PTGS2 | |
| SCHEMBL1179750 | 0.78 | RELA (0.74) | RELATP53TDP1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881954-B1 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE | TEVA PHARMA (IL) | 2009-09-16 | — | — | EP | disclosed |
| US-7250533-B2 | Process for preparing Cinacalcet hydrochloride | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2007-07-31 | — | — | US | disclosed |
| US-20070043243-A1 | Process for preparing Cinacalcet hydrochloride | TEVA PHARMACEUTICALS USA, INC. | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043243-A1 | Process for preparing Cinacalcet hydrochloride | SI, PRCP, CA9 | RELA 4637/4885TP53 2474/4885TDP1 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.