Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 5/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.33 |
| ▸ | ANPEP | P15144 | 5/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811225 | 0.85 | — | — | |
| SCHEMBL1953731 | 0.85 | — | — | |
| SCHEMBL1952217 | 0.85 | — | — | |
| Fluoride SCHEMBL5574127 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL5572501 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL5379077 | 0.83 | — | — | |
| Iodide SCHEMBL5573312 | 0.83 | — | — | |
| Bromide SCHEMBL5573171 | 0.83 | — | — | |
| Sulfuric Acid SCHEMBL3838035 | 0.82 | TP53 (0.38) | LAP3DPP4 | |
| SCHEMBL1724483 | 0.80 | NLRP3 (0.33) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413565-B1 | Method for optical resolution of 3-aminopentanenitrile | SALTIGO GMBH (DE) | 2009-09-30 | — | — | EP | disclosed |
| US-7193102-B2 | Process for the racemate resolution of 3-aminopentanenitrile | BAYER AKTIENGESELLSCHAFT (DE) | 2007-03-20 | — | — | US | disclosed |
| US-20040087811-A1 | Process for the racemate resolution of 3-aminopentanenitrile | LANXESS DEUTSCHLAND GMBH (DE) | 2004-05-06 | — | — | US | disclosed |
| EP-1413565-A2 | Method for optical resolution of 3-aminopentanenitrile | Bayer Chemicals AG (DE) | 2004-04-28 | — | — | EP | disclosed |