Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552754 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL5255040 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL145553 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL11816669 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL16718679 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL6920739 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL16698514 | 0.75 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7450023 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL28696312 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AGLATSHR | |
| SCHEMBL6743229 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091524-A2 | COMBINATION THERAPY FOR TREATING HEPATITIS C INFECTIONS | Achillion Pharmaceuticals, Inc. (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008076443-A2 | COMBINATION THERAPY FOR TREATING HEPATITIS C INFECTIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | claimed |