Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612544 | 0.96 | ALDH1A1 (0.49) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL8615325 | 0.91 | ALDH1A1 (0.47) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL8940199 | 0.89 | ALDH1A1 (0.44) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL8616953 | 0.89 | SLC22A2 (0.47) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL6463846 | 0.86 | ALDH1A1 (0.51) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL10532358 | 0.84 | NPC1 (0.59) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL28432596 | 0.82 | ALDH1A1 (0.55) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL27890501 | 0.81 | CRHBP (0.58) | ALDH1A1HTTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8940192 | 0.81 | CRHBP (0.54) | ALDH1A1HTTSMN1; SMN2MGLLL3MBTL1 | |
| SCHEMBL16698514 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068833-A1 | POLYMERIC COMPOSITIONS COMPRISING POLYISOPRENE | Ansell Limited (AU) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015070276-A1 | POLYMERIC COMPOSITIONS COMPRISING POLYISOPRENE | Ansell Limited (AU) | 2015-05-21 | — | — | WO | disclosed |
| CN-103435431-B | Method for realizing green synthesis of asymmetric thiocarbamide | UNIV CHANGZHOU | 2014-12-17 | — | — | CN | disclosed |
| CN-103435431-A | Method for realizing green synthesis of asymmetric thiocarbamide | UNIV CHANGZHOU | 2013-12-11 | — | — | CN | disclosed |