Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833602 | 1.00 | HTR6 (0.35) | HTR6ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL13567917 | 0.85 | ALDH1A1 (0.34) | HTR6ALDH1A1SLC6A4SLC6A3LMNA | |
| SCHEMBL3833886 | 0.81 | HTT (0.40) | ALDH1A1CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL3833882 | 0.81 | HTT (0.40) | ALDH1A1CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL3828428 | 0.80 | HTR6 (0.39) | HTR6ALDH1A1SLC6A4SLC6A3MAPK1 | |
| SCHEMBL3828431 | 0.80 | HTR6 (0.39) | HTR6ALDH1A1SLC6A4SLC6A3MAPK1 | |
| SCHEMBL3833984 | 0.79 | CNR1 (0.41) | HTR6ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL3833981 | 0.79 | CNR1 (0.41) | HTR6ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL1508787 | 0.78 | NPSR1 (0.36) | ALDH1A1SLC6A4SLC6A3LMNAKMT2A | |
| SCHEMBL13567931 | 0.78 | NPSR1 (0.36) | ALDH1A1SLC6A4SLC6A3LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | TP53, MDM2, TP53BP1 | HTR6 3973/4885ALDH1A1 1990/4885CYP1A2 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.