SCHEMBL3833778

SCHEMBL3833778

CCCOCC(O)COc1ccc(-c2ncnc(-c3ccc(OC)cc3)n2)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
MAPT P10636 5/20 0.41
ADRB3 P13945 2/20 0.39
KMT2A Q03164 3/20 0.39
NPC1 O15118 2/20 0.39
MEN1 O00255 2/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
GPR35 Q9HC97 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
CDK4 P11802 1/20 0.39
CASR P41180 1/20 0.38
MAPK1 P28482 3/20 0.37
ADRB2 P07550 2/20 0.37
ADRB1 P08588 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NOD2 Q9HC29 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277377 0.93 MAPT (0.43) LMNAHTTMAPTADRB3KMT2A
SCHEMBL7887570 0.89 MAPT (0.43) LMNAHTTMAPTADRB3NPC1
SCHEMBL15127483 0.88 CASR (0.42) LMNAHTTMAPTADRB3KMT2A
SCHEMBL3833773 0.86 LMNA (0.40) LMNAHTTMAPTADRB3KMT2A
SCHEMBL12755384 0.86 CASR (0.40) LMNAHTTMAPTADRB3KMT2A
SCHEMBL21514817 0.84 PLA2G4B (0.43) LMNAHTTMAPTADRB3NPC1
SCHEMBL21514725 0.83 NPC1 (0.46) LMNAHTTMAPTADRB3KMT2A
SCHEMBL8216433 0.83 LMNA (0.42) LMNAHTTMAPTKMT2AMEN1
SCHEMBL8775477 0.82 PLA2G4B (0.40) LMNAHTTMAPTADRB3KMT2A
SCHEMBL3832554 0.82 LMNA (0.39) LMNAHTTMAPTADRB3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2945601-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A LIPOPHILIC BENZOTRIAZOLE UV-SCREENING AGENT AND/OR A BIS-RESORCINYL TRIAZINE COMPOUND OREAL (FR) 2018-08-22 EP claimed
EP-2025324-B1 Method of Quenching Electronic Excitation of Chromophore-Containing Organic Molecules in Photoactive Compositions HALLSTAR INNOVATIONS CORP (US) 2013-08-14 EP claimed
EP-2025324-A1 Method of Quenching Electronic Excitation of Chromophore-Containing Organic Molecules in Photoactive Compositions HallStar Innovations Corp. (US) 2009-02-18 EP claimed
EP-3453379-A2 MICROPIGMENT MIXTURES Ciba Holding Inc. (CH) 2019-03-13 EP disclosed
EP-1796659-A2 SILVER DIHYDROGEN CITRATE COMPOSITIONS Pure Bioscience (US) 2007-06-20 EP disclosed
WO-2006029213-A2 SILVER DIHYDROGEN CITRATE COMPOSITIONS PURE BIOSCIENCE (US) 2006-03-16 WO disclosed