Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.55 |
| ▸ | RARB | P10826 | 13/20 | 0.55 |
| ▸ | RARA | P10276 | 12/20 | 0.55 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382998 | 0.87 | RARG (0.70) | RARGRARBRARA | |
| SCHEMBL382310 | 0.83 | RARG (0.80) | RARGRARBRARASLC6A9 | |
| SCHEMBL382355 | 0.81 | RARG (0.80) | RARGRARBRARASLC6A9 | |
| SCHEMBL382857 | 0.81 | RARG (0.80) | RARGRARBRARA | |
| SCHEMBL382810 | 0.81 | RARG (0.59) | RARGRARBRARASLC6A9MEN1 | |
| SCHEMBL382759 | 0.80 | RARB (0.57) | RARGRARBRARAHRH3HTT | |
| SCHEMBL383438 | 0.78 | RARG (0.78) | RARGRARBRARASLC6A9 | |
| SCHEMBL383163 | 0.77 | RARG (0.76) | RARGRARBRARASLC6A9 | |
| SCHEMBL382651 | 0.77 | RARG (0.60) | RARGRARBRARASLC6A9 | |
| SCHEMBL383393 | 0.77 | RARG (0.60) | RARGRARBRARASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |