Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 16/20 | 0.59 |
| ▸ | RARB | P10826 | 15/20 | 0.59 |
| ▸ | RARA | P10276 | 14/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383178 | 0.88 | RARG (0.75) | RARGRARBRARA | |
| SCHEMBL383438 | 0.86 | RARG (0.78) | RARGRARBRARASLC6A9 | |
| SCHEMBL382310 | 0.83 | RARG (0.80) | RARGRARBRARASLC6A9 | |
| SCHEMBL382355 | 0.82 | RARG (0.80) | RARGRARBRARASLC6A9 | |
| SCHEMBL383386 | 0.81 | RARG (0.55) | RARGRARBRARASLC6A9MEN1 | |
| SCHEMBL382857 | 0.81 | RARG (0.80) | RARGRARBRARA | |
| SCHEMBL382541 | 0.79 | RARG (0.77) | RARGRARBRARASLC6A9 | |
| SCHEMBL382688 | 0.78 | RARG (0.64) | RARGRARBRARASLC6A9 | |
| SCHEMBL382222 | 0.78 | RARG (0.66) | RARGRARBRARASLC6A9MEN1 | |
| SCHEMBL383193 | 0.77 | RARG (0.65) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |