Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 16/20 | 0.80 |
| ▸ | RARB | P10826 | 15/20 | 0.80 |
| ▸ | RARA | P10276 | 14/20 | 0.80 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382355 | 0.91 | RARG (0.80) | RARGRARBRARA | |
| SCHEMBL382692 | 0.89 | RARG (1.00) | RARGRARBRARATAAR1 | |
| SCHEMBL382310 | 0.88 | RARG (0.80) | RARGRARBRARA | |
| SCHEMBL383438 | 0.85 | RARG (0.78) | RARGRARBRARA | |
| SCHEMBL382093 | 0.83 | RARG (0.79) | RARGRARBRARATAAR1 | |
| SCHEMBL383386 | 0.81 | RARG (0.55) | RARGRARBRARA | |
| SCHEMBL382810 | 0.81 | RARG (0.59) | RARGRARBRARA | |
| SCHEMBL382434 | 0.80 | RARG (0.64) | RARGRARBRARA | |
| SCHEMBL382479 | 0.80 | RARG (1.00) | RARGRARBRARA | |
| SCHEMBL382222 | 0.80 | RARG (0.66) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |