Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832947 | 0.73 | NR3C1 (0.47) | PDE4APDE4BPDE4CPDE4DGFER | |
| SCHEMBL8354029 | 0.72 | GAA (0.58) | PDE4APDE4BPDE4CPDE4DGFER | |
| SCHEMBL6813892 | 0.72 | NR3C1 (0.53) | PDE4APDE4BPDE4CPDE4DNR3C1 | |
| SCHEMBL23003290 | 0.72 | NR3C1 (0.46) | PDE4APDE4BPDE4CPDE4DGFER | |
| SCHEMBL9513188 | 0.70 | GFER (0.57) | PDE4APDE4BPDE4CPDE4DGFER | |
| SCHEMBL18464323 | 0.70 | NR3C1 (0.47) | PDE4APDE4BPDE4CPDE4DGFER | |
| SCHEMBL28645245 | 0.69 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL28645243 | 0.69 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL30823798 | 0.69 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL11702699 | 0.69 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102168-A1 | ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-09-23 | — | — | EP | disclosed |
| EP-2079708-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | Bayer HealthCare AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008046527-A1 | ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008046527-A1 | ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008043533-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043533-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |