Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835749 | 0.98 | LMNA (0.56) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL7650406 | 0.96 | TSHR (0.50) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL3834688 | 0.92 | LMNA (0.61) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL27611225 | 0.91 | LMNA (0.67) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL3834694 | 0.91 | LMNA (0.67) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL3835895 | 0.91 | LMNA (0.67) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL27593161 | 0.91 | LMNA (0.67) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL3835751 | 0.90 | LMNA (0.64) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3836318 | 0.89 | LMNA (0.48) | LMNAAKR1B1GPR84PPARGPPARD | |
| SCHEMBL12804115 | 0.88 | TSHR (0.48) | LMNAAKR1B1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |