Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | FABP4 | P15090 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593161 | 1.00 | LMNA (0.67) | LMNAGPR84PPARGPPARDPPARA | |
| SCHEMBL3834694 | 1.00 | LMNA (0.67) | LMNAGPR84PPARGPPARDPPARA | |
| SCHEMBL27611225 | 1.00 | LMNA (0.67) | LMNAGPR84PPARGPPARDPPARA | |
| SCHEMBL3835749 | 0.93 | LMNA (0.56) | LMNAGPR84PPARGPPARDPPARA | |
| SCHEMBL27593159 | 0.92 | LMNA (0.77) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL3835899 | 0.92 | LMNA (0.77) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL3834695 | 0.92 | LMNA (0.77) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11614143 | 0.92 | LMNA (0.77) | LMNATSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL27611224 | 0.92 | LMNA (0.77) | LMNATSHRALDH1A1KMT2AMEN1 | |
| Acetic Acid SCHEMBL8011829 | 0.91 | LMNA (0.69) | LMNATSHRALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| CN-100516018-C | Double esters | PHOTOCURE ASA (NO) | 2009-07-22 | — | — | CN | disclosed |
| CN-1589254-A | Double esters | PHOTOCURE ASA (NO) | 2005-03-02 | — | — | CN | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |