Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSC | P53634 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810189 | 1.00 | CTSL (0.52) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3806486 | 0.95 | CTSL (0.53) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3810449 | 0.91 | RORC (0.46) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3811448 | 0.91 | RORC (0.46) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3811496 | 0.89 | CTSL (0.54) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3810727 | 0.87 | CTSL (0.51) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3808181 | 0.86 | CTSL (0.52) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3811330 | 0.86 | CTSL (0.42) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3810367 | 0.86 | CTSL (0.53) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3815681 | 0.86 | CTSL (0.55) | CTSLCTSSCTSKCTSCCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129365-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | WO | claimed |