Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419644 | 1.00 | MAPT (0.44) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL13504583 | 0.97 | MAPT (0.43) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL14403357 | 0.83 | ACHE (0.43) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL17508132 | 0.81 | ACHE (0.42) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL31469262 | 0.79 | AOC3 (0.45) | ALDH1A1GAASMN1; SMN2KDM4EACHE | |
| SCHEMBL27930560 | 0.79 | ACHE (0.40) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL4660214 | 0.79 | AOC3 (0.45) | ALDH1A1GAASMN1; SMN2KDM4EACHE | |
| SCHEMBL7690206 | 0.79 | MAPT (0.46) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL17425301 | 0.79 | ACHE (0.40) | MAPTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL65263 | 0.78 | MAPT (0.55) | MAPTALDH1A1GAASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585895-A | Processes for the preparation of mixed squaraine compositions | XEROX CORPORATION (US) | 1986-04-29 | — | — | US | claimed |
| EP-4446310-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | Asahi Kasei Kabushiki Kaisha (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-117964493-A | Synthesis method of N-methyl o-fluoroaniline | 湖南速博生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117482074-A | Anti-inflammatory composition comprising N-benzyl-N-methyl-dec-1-amine or derivative thereof as active ingredient | 釜山大学校产学协力团 | 2024-02-02 | — | — | CN | disclosed |
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2023106377-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | 旭化成株式会社 | 2023-06-15 | — | — | WO | disclosed |
| CN-111662185-B | Synthesis method of N-methyl o-fluoroaniline | 江苏富鼎化学有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-112851518-B | Synthesis method of N-methyl o-fluoroaniline | 江苏中旗科技股份有限公司 | 2023-02-14 | — | — | CN | disclosed |
| US-20220223790-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2022-07-14 | — | — | US | disclosed |
| WO-2021214315-A1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2021-10-28 | — | — | WO | disclosed |
| US-4746756-A | Photoconductive imaging members with novel fluorinated squaraine compounds | XEROX CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4621038-A | Photoconductive imaging members with novel symmetrical fluorinated squaraine compounds | XEROX CORPORATION (US) | 1986-11-04 | — | — | US | disclosed |
| US-4606986-A | Electrophotographic elements containing unsymmetrical squaraines | XEROX CORPORATION (US) | 1986-08-19 | — | — | US | disclosed |
| US-4585895-A | Processes for the preparation of mixed squaraine compositions | XEROX CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0146301-A1 | Process for synthesizing squaraine compositions | XEROX CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |
| EP-0144206-A2 | Process for synthesising squaraine compositions | XEROX CORPORATION (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4523035-A | BLUE AND GREEN PIGMENTS | XEROX CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4521621-A | Novel squarine systems | XEROX CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-4500715-A | CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| US-4268438-A | Cationic 1,3,4-thiadiazole dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | IKZF1, IKZF3, IKZF2 | MAPT 1369/4885ALDH1A1 4344/4885GAA 2982/4885 |
| US-20220223790-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SLCO2A1, SLCO4C1, TMEM109 | MAPT 2214/4885ALDH1A1 148/4885GAA 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.