SCHEMBL383523

SCHEMBL383523

[CH2]CC(CCC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL385914 0.84
SCHEMBL385374 0.82 OPRM1 (0.37)
SCHEMBL4486364 0.82
SCHEMBL21722536 0.82
SCHEMBL385818 0.81
SCHEMBL7439501 0.80 ZDHHC7 (0.38)
SCHEMBL386111 0.80 ZDHHC7 (0.38)
SCHEMBL8933419 0.80 ZDHHC7 (0.38)
SCHEMBL4508770 0.80 ZDHHC7 (0.38)
SCHEMBL7194789 0.80 ZDHHC7 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3191471-B1 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2020-03-11 EP disclosed
EP-2970215-B1 PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY ABBVIE DEUTSCHLAND (DE) 2019-04-17 EP disclosed
US-10202345-B2 Substituted azaspiro(4.5)decane derivatives GRUENENTHAL GMBH (DE) 2019-02-12 US disclosed
EP-3169666-B1 SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES GRUENENTHAL GMBH (DE) 2018-06-06 EP disclosed
EP-3169665-B1 SUBSTITUTED AZA-SPIRO(4.5)DECANE DERIVATIVES GRUENENTHAL GMBH (DE) 2018-05-09 EP disclosed
US-20170210734-A1 Substituted Azaspiro(4.5)Decane Derivatives GRUENENTHAL GMBH (DE) 2017-07-27 US disclosed
EP-3191471-A1 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY AbbVie Deutschland GmbH & Co. KG (DE) 2017-07-19 EP disclosed
EP-3169665-A1 SUBSTITUTED AZA-SPIRO(4.5)DECAN-DERIVATIVES Grünenthal GmbH (DE) 2017-05-24 EP disclosed
EP-3169666-A1 SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES Grünenthal GmbH (DE) 2017-05-24 EP disclosed
US-9656955-B2 Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy ABBVIE INC. (US) 2017-05-23 US disclosed
EP-0148934-A1 LOW TEMPERATURE, STORAGE STABLE MIXTURES OF POLYESTER PREPOLYMERS AND FLOW MODIFIERS Hostettler, Fritz (US) 1985-07-24 EP disclosed
US-4524102-A NONHYDROXYL FLOW MODIFIER FIRST NATIONAL BANK OF TOMS RIVER, N.J., THE 1985-06-18 US disclosed
US-4496683-A INCREASED SCORCH DELAY, FASTER CURE RATE AND IMPROVED REVERSION RESISTANCE MONSANTO COMPANY (US) 1985-01-29 US disclosed
WO-1985000177-A1 LOW TEMPERATURE, STORAGE STABLE MIXTURES OF POLYESTER PREPOLYMERS AND FLOW MODIFIERS PIRRI, JAQUELYN, P. (US) 1985-01-17 WO disclosed
EP-0130090-A2 Low temperature, storage stable mixtures of polyester prepolymers and flow modifiers Hostettler, Fritz (US) 1985-01-02 EP disclosed
US-4469616-A NON-HYDROXYL CONTAINING FIRST NATIONAL BANK OF TOMS RIVER, N.J., THE 1984-09-04 US disclosed
EP-0104157-A1 Rubber compositions containing a vulcanization system alterative Monsanto Company (US) 1984-03-28 EP disclosed
US-4099014-A BLOOD PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1978-07-04 US disclosed
US-4033989-A 9-Deoxy-PGF2 Analogs THE UPJOHN COMPANY (US) 1977-07-05 US disclosed
US-4016184-A PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1977-04-05 US disclosed