Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980728 | 1.00 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A | |
| SCHEMBL5147750 | 0.87 | RAB9A (0.37) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A | |
| SCHEMBL5264737 | 0.82 | TRPV1 (0.37) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A | |
| SCHEMBL5149503 | 0.82 | TRPV1 (0.37) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A | |
| SCHEMBL5149330 | 0.80 | PTGER4 (0.35) | CSNK2A2CSNK2BMEN1KMT2AMAPT | |
| SCHEMBL2980724 | 0.76 | MEN1 (0.42) | MEN1KMT2ANPSR1MAPTKDM4E | |
| SCHEMBL5262210 | 0.76 | MEN1 (0.42) | MEN1KMT2ANPSR1MAPTKDM4E | |
| SCHEMBL5259518 | 0.76 | MAPT (0.40) | CSNK2A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL2980731 | 0.75 | MEN1 (0.43) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A | |
| SCHEMBL27607194 | 0.75 | SYK (0.45) | CSNK2A1CSNK2A2CSNK2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531549-B2 | Phenylalanine enamide derivatives | UCB PHARMA, S.A. (BE) | 2009-05-12 | — | — | US | disclosed |
| US-20070027174-A1 | Phenylalanine Enamide Derivatives | CELLTECH R&D LIMITED | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027174-A1 | Phenylalanine Enamide Derivatives | PAH, HRH3, AGTR2 | CSNK2A1 457/4885CSNK2A2 439/4885CSNK2B 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.