Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576535 | 0.90 | HTT (0.68) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL30210988 | 0.83 | LCK (0.53) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL15074289 | 0.83 | HTT (0.50) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL3836141 | 0.82 | MAPT (0.64) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL14780513 | 0.82 | HTT (0.81) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL31175997 | 0.82 | HTT (0.81) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL3461530 | 0.80 | KDM4E (0.57) | KDM4EHPGDHSD17B10LMNACYP3A4 | |
| SCHEMBL23511720 | 0.80 | ALDH1A1 (0.52) | KDM4EHPGDHSD17B10CYP3A4MAPT | |
| Water SCHEMBL28292285 | 0.78 | ALDH1A1 (0.50) | KDM4EHPGDHSD17B10CYP3A4MAPT | |
| SCHEMBL69624 | 0.78 | MAOB (0.59) | KDM4EHPGDHSD17B10LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | claimed |
| US-8505730-B2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | JR CHEM, LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120312717-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | JR CHEM, LLC (US) | 2012-12-13 | — | — | US | disclosed |
| US-8273791-B2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | JR CHEM, LLC (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2087880-A2 | Compositions, kits and regimens for the treatment of skin, especially décolletage | Jr Chem, LLC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-20090176876-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | JR CHEM, LLC (US) | 2009-07-09 | — | — | US | disclosed |
| US-6960347-B2 | Composition based on N-cholesteryloxycarbonyl-4-para-aminophenol and hydroquinone or one of its derivatives | L'OREAL (FR) | 2005-11-01 | — | — | US | disclosed |
| US-20010036446-A1 | Composition based on N-cholesteryloxycarbonyl-4-para-aminophenol and hydroquinone or one of its derivatives | L'OREAL (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176876-A1 | COMPOSITIONS, KITS AND REGIMENS FOR THE TREATMENT OF SKIN, ESPECIALLY DECOLLETAGE | RARG, RARA, RXRG | KDM4E 3387/4885HPGD 92/4885HSD17B10 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.