Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777417 | 1.00 | RXFP1 (0.40) | RXFP1ALDH1A1TSHRGAAHBB | |
| SCHEMBL3835893 | 1.00 | RXFP1 (0.40) | RXFP1ALDH1A1TSHRGAAHBB | |
| SCHEMBL3835889 | 1.00 | RXFP1 (0.40) | RXFP1ALDH1A1TSHRGAAHBB | |
| SCHEMBL7775621 | 0.80 | TSHR (0.40) | RXFP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL7777453 | 0.80 | TSHR (0.40) | RXFP1ALDH1A1TSHRGAAPOLB | |
| SCHEMBL9264763 | 0.79 | EPHX1 (0.42) | ALDH1A1TSHRGAAPOLBKDM4E | |
| SCHEMBL28924946 | 0.77 | EPHX1 (0.41) | ALDH1A1TSHRGAAPOLBKDM4E | |
| SCHEMBL30349456 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRGAAPOLBKDM4E | |
| SCHEMBL7764706 | 0.75 | EPHX1 (0.56) | RXFP1ALDH1A1TSHRHBBHSD17B10 | |
| SCHEMBL7764709 | 0.75 | EPHX1 (0.56) | RXFP1ALDH1A1TSHRHBBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288201-B1 | Optically active maleimide derivatives, optically active polymaleimide derivatives, production method thereof, separating agent using the same derivative, and method for separating optically active compounds using the same agent | TOSOH CORP (JP) | 2009-10-07 | — | — | EP | disclosed |
| US-6777526-B2 | OPTICAL RESOLUTION AGENT OF AN OPTICALLY ACTIVE POLYMER DERIVED FROM AN N-(1-CYCLOHEXYLALKYL)MALEIMIDE TYPE MONOMER OF GIVEN FORMULA | TOSOH CORPORATION (JP) | 2004-08-17 | — | — | US | disclosed |
| EP-1288201-A1 | Optically active maleimide derivatives, optically active polymaleimide derivatives, production method thereof, separating agent using the same derivative, and method for separating optically active compounds using the same agent | Tosoh Corporation (JP) | 2003-03-05 | — | — | EP | disclosed |
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |