Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775621 | 1.00 | TSHR (0.40) | TSHRALDH1A1GAAMAPK1ALOX15 | |
| SCHEMBL30349456 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1GAAALOX15HDAC4 | |
| SCHEMBL7777417 | 0.80 | RXFP1 (0.40) | TSHRALDH1A1GAARXFP1PDE5A | |
| SCHEMBL3835892 | 0.80 | RXFP1 (0.40) | TSHRALDH1A1GAARXFP1PDE5A | |
| SCHEMBL3835889 | 0.80 | RXFP1 (0.40) | TSHRALDH1A1GAARXFP1PDE5A | |
| SCHEMBL3835893 | 0.80 | RXFP1 (0.40) | TSHRALDH1A1GAARXFP1PDE5A | |
| SCHEMBL7772636 | 0.78 | TSHR (0.61) | TSHRALDH1A1MAPK1POLBABCB1 | |
| SCHEMBL16303826 | 0.78 | TSHR (0.61) | TSHRALDH1A1MAPK1POLBABCB1 | |
| SCHEMBL9488854 | 0.78 | TSHR (0.61) | TSHRALDH1A1MAPK1POLBABCB1 | |
| SCHEMBL7770452 | 0.78 | TSHR (0.61) | TSHRALDH1A1MAPK1POLBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |