Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.56 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611224 | 1.00 | LMNA (0.77) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL3834695 | 1.00 | LMNA (0.77) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL11614143 | 1.00 | LMNA (0.77) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL27593159 | 1.00 | LMNA (0.77) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| Acetic Acid SCHEMBL10783410 | 0.94 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| Acetic Acid SCHEMBL8011829 | 0.94 | LMNA (0.69) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL3834694 | 0.92 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PAM | |
| SCHEMBL27593161 | 0.92 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PAM | |
| SCHEMBL27611225 | 0.92 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PAM | |
| SCHEMBL3835895 | 0.92 | LMNA (0.67) | LMNAMAPTMAPK1ALDH1A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |