Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382681 | 0.94 | ITGB3 (0.44) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL383595 | 0.86 | ITGB3 (0.49) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL382101 | 0.85 | ITGB3 (0.46) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383243 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL27472952 | 0.80 | ITGB3 (0.42) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382680 | 0.80 | ITGB3 (0.51) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL382581 | 0.79 | ITGB3 (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL383237 | 0.79 | ITGB3 (0.46) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL382299 | 0.79 | ITGB3 (0.42) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL383235 | 0.78 | ITGB3 (0.48) | ITGB3ITGAVITGA2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |