Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 11/20 | 0.54 |
| ▸ | KDR | P35968 | 11/20 | 0.54 |
| ▸ | CDK2 | P24941 | 8/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840665 | 0.82 | KDR (0.60) | AURKAKDR | |
| SCHEMBL3836057 | 0.80 | AURKA (0.57) | AURKAKDRCDK2 | |
| SCHEMBL3835801 | 0.77 | ELANE (0.37) | AURKAKDRELANE | |
| Hydrochloric Acid SCHEMBL3837341 | 0.72 | AURKA (0.56) | AURKAKDRCDK2 | |
| SCHEMBL5328900 | 0.71 | AURKA (1.00) | AURKAKDRCDK2 | |
| SCHEMBL14468698 | 0.65 | KDR (0.83) | AURKAKDR | |
| SCHEMBL5329803 | 0.63 | KDR (0.77) | AURKAKDR | |
| SCHEMBL14216504 | 0.62 | MAPKAPK2 (0.45) | — | |
| SCHEMBL24667787 | 0.61 | HPGD (0.44) | AURKAKDR | |
| SCHEMBL23051433 | 0.61 | MAPT (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |