Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835801 | 0.79 | ELANE (0.37) | AURKAKDR | |
| SCHEMBL3047993 | 0.77 | DUT (0.34) | DUT | |
| SCHEMBL3039536 | 0.75 | DUT (0.34) | DUT | |
| SCHEMBL5326703 | 0.70 | PREP (0.37) | AURKAKDR | |
| SCHEMBL3835796 | 0.68 | MAP3K9 (0.38) | AURKAKDR | |
| SCHEMBL9934160 | 0.67 | ALDH1A1 (0.37) | DUT | |
| SCHEMBL20568979 | 0.66 | APP (0.41) | DUT | |
| SCHEMBL3836782 | 0.66 | AURKA (0.31) | AURKAKDR | |
| SCHEMBL3839735 | 0.66 | — | — | |
| SCHEMBL3839919 | 0.66 | GCK (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |