Chloroxylenol

Chloroxylenol

SCHEMBL383630

Cc1cc(O)cc(C)c1Cl.Cc1ccc(Cl)c(O)c1C

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.61
CHRM1 P11229 1/20 0.61
ALOX15 P16050 1/20 0.61
MAOA P21397 1/20 0.61
TBXA2R P21731 1/20 0.61
ADRA1A P35348 1/20 0.61
HTR2B P41595 1/20 0.61
HSD17B10 Q99714 3/20 0.40
ESR2 Q92731 4/20 0.39
ESR1 P03372 3/20 0.39
HPGD P15428 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
SIRT1 Q96EB6 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34164 0.85 DPP4 (0.39) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL28812975 0.85 DPP4 (0.39) CYP3A4CHRM1ALOX15MAOATBXA2R
Chloroxylenol SCHEMBL5569330 0.79 CYP3A4 (0.73) CYP3A4CHRM1ALOX15MAOATBXA2R
Phenol SCHEMBL7149052 0.78 TDP1 (0.44) CHRM1ALOX15TBXA2RHSD17B10ESR2
Chloroxylenol SCHEMBL7950378 0.78 CYP3A4 (1.00) CYP3A4CHRM1ALOX15MAOATBXA2R
Chloroxylenol SCHEMBL34163 0.78 CYP3A4 (1.00) CYP3A4CHRM1ALOX15MAOATBXA2R
Alcohol SCHEMBL28660521 0.78 DPP4 (0.34) CYP3A4HSD17B10ESR2ESR1SIRT1
Chloroxylenol SCHEMBL28179844 0.76 CYP3A4 (0.94) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL1362999 0.74 TRPA1 (0.40) CYP3A4HSD17B10ESR2ESR1ALDH1A1
SCHEMBL10340010 0.74 GAA (0.32) CYP3A4ALDH1A1GAAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238183-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-07-18 US disclosed
EP-4363062-A1 TOPICAL COMPOSITION AGAINST FINE LINES AND WRINKLES Mary Kay, Inc. (US) 2024-05-08 EP disclosed
WO-2024088925-A1 FLAVONOID COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2024-05-02 WO disclosed
WO-2024073299-A2 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME MARY KAY INC. (US) 2024-04-04 WO disclosed
WO-2024054923-A2 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2024-03-14 WO disclosed
WO-2024044773-A1 NUTRACEUTICAL COMPOSITIONS AND METHODS FOR USING SAME MARY KAY INC. (US) 2024-02-29 WO disclosed
US-20240058238-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-02-22 US disclosed
EP-4304385-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT Firmenich Incorporated (US) 2024-01-17 EP disclosed
WO-2024011086-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2024-01-11 WO disclosed
US-20240009097-A1 COSMETIC COMPOSITION MARY KAY INC. (US) 2024-01-11 US disclosed
WO-2007126777-A2 ANTI-MICROBIAL HAND TOWEL WITH TIME-DELAY CHROMATIC TRANSFER INDICATOR AND ABSORBENCY RATE DELAY GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2007-11-08 WO disclosed
US-20070237807-A1 Anti-microbial hand towel with time-delay chromatic transfer indicator and absorbency rate delay GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2007-10-11 US disclosed
WO-2007067873-A2 LOTION-TREATED TISSUE AND TOWEL GEORGIA-PACIFIC CONSUMER PRODUCTS LP (US) 2007-06-14 WO disclosed
US-20070124872-A1 Method of coloring with capped diazotized compound and coupling component CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
US-20070087041-A1 Waterless Lotion and Lotion-Treated Substrate FORT JAMES CORPORATION (US) 2007-04-19 US disclosed
US-7169400-B2 Waterless lotion and lotion-treated substrate FORT JAMES CORPORATION (US) 2007-01-30 US disclosed
US-20060110432-A1 Lotion-treated tissue and towel GPCP IP HOLDINGS LLC 2006-05-25 US disclosed
US-20030211124-A1 Waterless lotion and lotion-treated substrate FORT JAMES CORPORATION 2003-11-13 US disclosed
EP-1360954-A2 Waterless lotion and lotion-treated substrate Fort James Corporation (US) 2003-11-12 EP disclosed
US-5871763-A EMOLLIENTS FOR SKINS FORT JAMES CORPORATION (US) 1999-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070124872-A1 Method of coloring with capped diazotized compound and coupling component TYR, C5, C9 CYP3A4 656/4885CHRM1 271/4885ALOX15 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.