Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507153 | 0.80 | POLB (0.34) | POLBCREBBP | |
| SCHEMBL3785748 | 0.77 | — | — | |
| SCHEMBL19049167 | 0.65 | — | — | |
| SCHEMBL5813243 | 0.62 | — | — | |
| SCHEMBL298185 | 0.62 | CRHBP (0.34) | POLB | |
| SCHEMBL19027439 | 0.61 | — | — | |
| SCHEMBL277444 | 0.61 | — | — | |
| SCHEMBL697810 | 0.60 | NOTUM (0.31) | — | |
| SCHEMBL8888893 | 0.59 | CRHBP (0.33) | — | |
| SCHEMBL8888317 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094670-A1 | HETEROCYCLYC SULFONAMIDES HAVING EDG-I ANTAGONISTIC ACTIVITY | AstraZeneca AB (SE) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008056150-A1 | HETEROCYCLYC SULFONAMIDES HAVING EDG-I ANTAGONISTIC ACTIVITY | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | WO | disclosed |