Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298642 | 0.87 | CRHBP (0.35) | CRHBPCRHR2 | |
| SCHEMBL30211022 | 0.74 | — | — | |
| SCHEMBL3441740 | 0.69 | — | — | |
| SCHEMBL8888317 | 0.69 | — | — | |
| SCHEMBL28912585 | 0.69 | — | — | |
| SCHEMBL3797084 | 0.66 | KMT2A (0.36) | — | |
| SCHEMBL3790098 | 0.65 | CRHBP (0.30) | CRHBPCRHR2 | |
| SCHEMBL298185 | 0.64 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL29913840 | 0.63 | PIK3CD (0.31) | — | |
| SCHEMBL697810 | 0.63 | NOTUM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |