Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383731 | 0.93 | TSHR (0.32) | TSHR | |
| SCHEMBL4818972 | 0.91 | TSHR (0.31) | TSHR | |
| SCHEMBL10030503 | 0.89 | TSHR (0.35) | TSHR | |
| SCHEMBL10158968 | 0.88 | — | — | |
| SCHEMBL19325220 | 0.87 | — | — | |
| SCHEMBL12733567 | 0.86 | TSHR (0.42) | TSHR | |
| SCHEMBL16504168 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL2621446 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL14136628 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL15935503 | 0.85 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393157-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | CHIRON AS (NO) | 2023-12-07 | — | — | US | disclosed |
| US-11827667-B2 | Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof | UNIVERSITY OF MIYAZAKI (JP) | 2023-11-28 | — | — | US | disclosed |
| US-20230332210-A1 | REPORTER AND USE THEREOF | SFC CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230332210-A1 | REPORTER AND USE THEREOF | SFC CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| WO-2023177808-A1 | MODIFIED GAPMER OLIGOMERS AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-4214216-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | Chiron AS (NO) | 2023-07-26 | — | — | EP | disclosed |
| EP-3125946-B1 | COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES | APOSENSE LTD (IL) | 2022-12-07 | — | — | EP | disclosed |
| US-11318206-B2 | Compounds and methods for trans-membrane delivery of molecules | APOSENSE LTD (IL) | 2022-05-03 | — | — | US | disclosed |
| WO-2022058192-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | CHIRON AS (NO) | 2022-03-24 | — | — | WO | disclosed |
| US-9499572-B2 | Phosphatidylalkanols and compositions thereof | Pethmark AB (SE) | 2016-11-22 | — | — | US | disclosed |
| US-20160052946-A1 | NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF | Pethmark AB (SE) | 2016-02-25 | — | — | US | disclosed |
| US-20150203847-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | ALNYLAM PHARMACEUTICALS INC (US) | 2015-07-23 | — | — | US | disclosed |
| US-8962580-B2 | Chemical modifications of monomers and oligonucleotides with cycloaddition | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120035115-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-02-09 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7855293-B2 | Fluorescent dyes such as 2-(4-acetanilino-1,3-butadieneyl)-3-spiro-1'-cyclohexan-1-(4-sulfobutyl)-3H -indolium hydroxide metal salts which couple biological materials without loss of fluorescence due to self-quenching | HAALCK LUTZ | 2010-12-21 | — | — | US | disclosed |
| US-7855293-B2 | Fluorescent dyes such as 2-(4-acetanilino-1,3-butadieneyl)-3-spiro-1'-cyclohexan-1-(4-sulfobutyl)-3H -indolium hydroxide metal salts which couple biological materials without loss of fluorescence due to self-quenching | HAALCK LUTZ | 2010-12-21 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203847-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | DNMT1, LCK, MCTS1 | TSHR 3178/4885 |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | TSHR 2990/4885 |
| US-20160052946-A1 | NOVEL PHOSPHATIDYLALKANOLS AND COMPOSITIONS THEREOF | PHOSPHO1, SGMS1, DEGS1 | TSHR 1894/4885 |
| US-20230393157-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | PHOSPHO1, SGMS2, SGMS1 | TSHR 4269/4885 |
| US-11827667-B2 | Production method for guanosine derivative having fluorine atom-containing functional group at position 8 and application thereof | RNMT, FBL, NOP2 | TSHR 1340/4885 |
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | STING1, CGAS, IRF3 | TSHR 4157/4885 |
| US-20120035115-A1 | CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION | DNMT1, LCK, MCTS1 | TSHR 3178/4885 |
| US-11318206-B2 | Compounds and methods for trans-membrane delivery of molecules | ABCB4, LNPK, MBOAT1 | TSHR 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.