Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837461 | 1.00 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9694281 | 0.82 | ALDH3A1 (0.56) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11837114 | 0.80 | ATM (0.50) | MAPTALDH1A1LMNAPTGS2BACE1 | |
| SCHEMBL11837128 | 0.80 | ATM (0.50) | MAPTALDH1A1LMNAPTGS2BACE1 | |
| SCHEMBL12367389 | 0.78 | TSHR (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3933622 | 0.77 | BACE1 (0.40) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3933619 | 0.77 | BACE1 (0.40) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11834613 | 0.77 | BACE1 (0.50) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11834600 | 0.77 | BACE1 (0.50) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17968829 | 0.76 | MAPT (0.44) | MAPTALDH1A1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |