Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791340 | 0.88 | ALDH3A1 (0.56) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3837461 | 0.82 | MAPT (0.51) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3837463 | 0.82 | MAPT (0.51) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2502259 | 0.82 | MAPT (0.62) | ALDH3A1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL14180498 | 0.79 | TDP1 (0.55) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3835000 | 0.79 | MAPT (0.67) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16284334 | 0.79 | ALDH1A1 (0.46) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28379902 | 0.78 | ALDH1A1 (0.67) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6202561 | 0.78 | MAPT (0.42) | ALDH3A1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6081882 | 0.78 | GPR35 (0.51) | ALDH3A1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-B1 | AMINOIMIDAZOQUINOLINE DERIVATIVES | Bristol-Myers Squibb Company (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |
| US-4701459-A | 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |