Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3838572 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL29432545 | 0.98 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL601324 | 0.98 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL29868203 | 0.98 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL2858131 | 0.97 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| Biphenyl SCHEMBL1142810 | 0.94 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL5147506 | 0.93 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4EMAPK1TSHR | |
| SCHEMBL12746074 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL4617722 | 0.91 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 | |
| SCHEMBL4022678 | 0.91 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPK1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1376231-B1 | Photosensitive polymer composition, method of forming relief patterns, and electronic equipment | HITACHI CHEM DUPONT MICROSYS (JP) | 2009-04-01 | — | — | EP | disclosed |