Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432545 | 0.92 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| SCHEMBL29868203 | 0.92 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| SCHEMBL601324 | 0.92 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| Iodide SCHEMBL3838568 | 0.91 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| SCHEMBL2858131 | 0.91 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| Iodide SCHEMBL3838572 | 0.91 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| SCHEMBL12746074 | 0.90 | ALDH1A1 (0.46) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| SCHEMBL5147506 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| Biphenyl SCHEMBL1142810 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA | |
| SCHEMBL4617722 | 0.85 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EALDH1A1MAPK1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090191476-A1 | THERMOPLASTIC MATERIALS COMPRISING CHARGE TRANSFER AGENTS AND PHOTO ACID GENERATING AGENTS | PROCTER & GAMBLE COMPANY, THE | 2009-07-30 | — | — | US | claimed |
| WO-2009093192-A1 | THERMOPLASTIC MATERIALS COMPRISING CHARGE TRANSFER AGENTS AND PHOTO ACID GENERATING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2009-07-30 | — | — | WO | claimed |
| EP-2083324-A1 | Thermoplastic materials comprising charge transfer agents and photo acid generating agents | The Procter and Gamble Company (US) | 2009-07-29 | — | — | EP | claimed |
| US-20090191476-A1 | THERMOPLASTIC MATERIALS COMPRISING CHARGE TRANSFER AGENTS AND PHOTO ACID GENERATING AGENTS | PROCTER & GAMBLE COMPANY, THE | 2009-07-30 | — | — | US | disclosed |
| EP-2083324-A1 | Thermoplastic materials comprising charge transfer agents and photo acid generating agents | The Procter and Gamble Company (US) | 2009-07-29 | — | — | EP | disclosed |