Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | ACLY | P53396 | 8/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562156 | 0.69 | PPARG (0.61) | PPARGPPARAPPARDACLYHTR6 | |
| SCHEMBL2930588 | 0.69 | PTGS1 (0.38) | PPARGPPARAPPARDHTR6 | |
| SCHEMBL17422757 | 0.68 | PPARG (0.60) | PPARGPPARAPPARDACLY | |
| SCHEMBL3555924 | 0.67 | ACLY (0.66) | PPARGPPARAPPARDACLY | |
| SCHEMBL739191 | 0.67 | PPARG (0.58) | PPARGPPARAPPARDACLY | |
| SCHEMBL6774913 | 0.67 | PPARG (0.58) | PPARGPPARAPPARDACLY | |
| SCHEMBL6767107 | 0.67 | PPARG (0.55) | PPARGPPARAPPARDACLY | |
| SCHEMBL27713311 | 0.67 | PPARG (0.58) | PPARGPPARAPPARDACLY | |
| SCHEMBL16486237 | 0.66 | PPARG (0.71) | PPARGPPARAPPARDACLY | |
| SCHEMBL741459 | 0.66 | ACLY (0.64) | PPARGPPARAPPARDACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791537-B1 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE I | AVENTIS PHARMA INC (US) | 2009-10-14 | — | — | EP | claimed |