Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.58 |
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | PPARD | Q03181 | 5/20 | 0.58 |
| ▸ | ACLY | P53396 | 12/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739191 | 0.89 | PPARG (0.58) | PPARGPPARAPPARDACLY | |
| SCHEMBL3562156 | 0.82 | PPARG (0.61) | PPARGPPARAPPARDACLY | |
| SCHEMBL17422757 | 0.81 | PPARG (0.60) | PPARGPPARAPPARDACLY | |
| SCHEMBL3555924 | 0.80 | ACLY (0.66) | PPARGPPARAPPARDACLY | |
| SCHEMBL6424043 | 0.80 | MAPT (0.52) | PPARGPPARAPPARDACLY | |
| SCHEMBL16486237 | 0.79 | PPARG (0.71) | PPARGPPARAPPARDACLY | |
| SCHEMBL741459 | 0.79 | ACLY (0.64) | PPARGPPARAPPARDACLY | |
| SCHEMBL16486365 | 0.78 | PPARG (0.73) | PPARGPPARAPPARDACLY | |
| SCHEMBL4657662 | 0.78 | PPARG (0.70) | PPARGPPARAPPARDACLY | |
| SCHEMBL1858379 | 0.77 | PPARG (0.45) | PPARGPPARAPPARDACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716605-B2 | Indole derivatives having an antiviral activity | SHIONOGI & CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| CN-1142909-C | Indole derivatives with antiviral activity | ��Ұ����ҩ��ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| US-20030181499-A1 | Indole derivatives having an antiviral activity | FUJISHITA TOSHIO (JP) | 2003-09-25 | — | — | US | disclosed |
| US-6506787-B2 | Aids therapy | SHIONOGI & CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| US-20020019434-A1 | Indole derivatives having an antiviral activity | FUJISHITA TOSHIO (JP) | 2002-02-14 | — | — | US | disclosed |
| US-6333323-B1 | AS ANTI-HUMAN IMMUNODEFICIENCY VIRUS (HIV) DRUGS | SHIONOGI & CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| CN-1294580-A | Indole derivatives with antiviral activity | SHIONOGI & CO (JP) | 2001-05-09 | — | — | CN | disclosed |
| EP-1069111-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019434-A1 | Indole derivatives having an antiviral activity | IDO1, IDO2, RCOR1 | PPARG 3840/4885PPARA 3040/4885PPARD 3571/4885 |
| US-20030181499-A1 | Indole derivatives having an antiviral activity | IDO1, RCOR1, IDO2 | PPARG 3823/4885PPARA 3014/4885PPARD 3565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.