Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526908 | 0.82 | GAA (0.40) | LMNAGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL239634 | 0.80 | DRD2 (0.41) | HTTLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL237897 | 0.79 | SMN1; SMN2 (0.37) | HTTLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL239111 | 0.78 | KDM4E (0.46) | HTTSMN1; SMN2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL237525 | 0.77 | ALDH1A1 (0.58) | HTTLMNAGAAALDH1A1MAPT | |
| SCHEMBL16202022 | 0.76 | GAA (0.48) | HTTLMNAGAASMN1; SMN2ALDH1A1 | |
| Oxalic Acid SCHEMBL238027 | 0.76 | ALDH1A1 (0.41) | HTTLMNASMN1; SMN2ALDH1A1MAPT | |
| Oxalic Acid SCHEMBL238029 | 0.76 | ALDH1A1 (0.41) | HTTLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3837939 | 0.75 | SMN1; SMN2 (0.40) | HTTLMNAGAASMN1; SMN2ALDH1A1 | |
| Oxalic Acid SCHEMBL238865 | 0.74 | SMN1; SMN2 (0.38) | HTTLMNASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097394-A1 | 1,2,4-TRIAZOLE DERIVATIVES AS SIGMA RECEPTOR INHIBITORS | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-09-09 | — | — | EP | claimed |
| WO-2008055932-A1 | 1,2,4-TRIAZOLE DERIVATIVES AS SIGMA RECEPTOR INHIBITORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-05-15 | — | — | WO | claimed |