Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849410 | 0.93 | PPARG (0.40) | PPARGPPARAMAOAMAOBTP53 | |
| SCHEMBL3840711 | 0.92 | MAOA (0.33) | PPARGPPARAMAOAMAOBKDM4E | |
| SCHEMBL3841112 | 0.92 | PPARG (0.39) | PPARGPPARATP53SMPD1KDM4E | |
| SCHEMBL3841330 | 0.91 | PPARG (0.38) | PPARGPPARAMAOAMAOBTP53 | |
| SCHEMBL3843493 | 0.89 | PPARG (0.37) | PPARGPPARATP53S1PR2S1PR4 | |
| SCHEMBL3842931 | 0.88 | PPARA (0.43) | PPARGPPARATP53PPARDTLR7 | |
| SCHEMBL3845506 | 0.88 | S1PR1 (0.37) | PPARGPPARAMAOAMAOBSMPD1 | |
| SCHEMBL3849869 | 0.86 | PPARG (0.38) | PPARGPPARATP53KDM4ES1PR2 | |
| SCHEMBL3851231 | 0.85 | S1PR1 (0.35) | PPARGPPARAMAOAMAOBSMPD1 | |
| SCHEMBL3292854 | 0.85 | PPARA (0.42) | PPARGPPARAMAOAMAOBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |