Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851231 | 0.96 | S1PR1 (0.35) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3844823 | 0.91 | PPARG (0.42) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3840985 | 0.88 | PPARG (0.36) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3285318 | 0.86 | PPARG (0.41) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3288469 | 0.84 | TLR7 (0.34) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3845660 | 0.83 | S1PR1 (0.36) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3849410 | 0.81 | PPARG (0.40) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3840711 | 0.80 | MAOA (0.33) | S1PR1S1PR3S1PR2S1PR4PPARG | |
| SCHEMBL3284220 | 0.80 | MAPT (0.34) | PPARGPPARAPPARDTRPA1MAOA | |
| SCHEMBL3841112 | 0.80 | PPARG (0.39) | PPARGPPARAPPARDSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |