Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.48 |
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARD | Q03181 | 8/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845617 | 0.89 | PPARA (0.42) | PPARAPPARGPPARDADRB3 | |
| SCHEMBL3841460 | 0.79 | PPARA (0.59) | PPARAPPARGPPARDADRB3ALDH1A1 | |
| SCHEMBL3841065 | 0.75 | PPARA (0.45) | PPARAPPARGPPARDADRB3 | |
| SCHEMBL12328025 | 0.75 | ADRB3 (0.67) | PPARAPPARGPPARDADRB3ALDH1A1 | |
| SCHEMBL3840876 | 0.75 | ADRB3 (0.67) | PPARAPPARGPPARDADRB3ALDH1A1 | |
| SCHEMBL3848024 | 0.74 | ADRB3 (0.73) | PPARAPPARGPPARDADRB3ALDH1A1 | |
| SCHEMBL3843762 | 0.74 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL3285211 | 0.73 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL3842497 | 0.72 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL3844493 | 0.72 | PPARA (0.48) | PPARAPPARGPPARDADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |