Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.51 |
| ▸ | PPARG | P37231 | 16/20 | 0.51 |
| ▸ | PPARD | Q03181 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845272 | 0.90 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL3284441 | 0.90 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL3848677 | 0.90 | PPARG (0.41) | PPARAPPARGPPARD | |
| SCHEMBL3841939 | 0.87 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL3840282 | 0.87 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL3841197 | 0.85 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL3842224 | 0.82 | PPARA (0.62) | PPARAPPARGPPARD | |
| SCHEMBL3848511 | 0.81 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL3845856 | 0.81 | PPARG (0.44) | PPARAPPARGPPARD | |
| SCHEMBL3842218 | 0.81 | PPARA (0.36) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |