Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842218 | 0.91 | PPARA (0.36) | PPARGPPARAPPARD | |
| SCHEMBL3845856 | 0.91 | PPARG (0.44) | PPARGPPARAPPARDS1PR4S1PR1 | |
| SCHEMBL3841402 | 0.90 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL3849916 | 0.88 | PPARA (0.41) | PPARGPPARAPPARDHTR2CSLC6A4 | |
| SCHEMBL3842292 | 0.86 | PPARG (0.39) | PPARGPPARAPPARDS1PR4S1PR1 | |
| SCHEMBL3284441 | 0.83 | PPARA (0.45) | PPARGPPARAPPARDTSHR | |
| SCHEMBL3841400 | 0.83 | PPARA (0.49) | PPARGPPARAPPARDPLA2G4BCNR1 | |
| SCHEMBL3842663 | 0.82 | PPARA (0.40) | PPARGPPARAPPARD | |
| SCHEMBL3840362 | 0.81 | PPARA (0.43) | PPARGPPARAPPARDS1PR4S1PR1 | |
| SCHEMBL3845272 | 0.80 | PPARA (0.53) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |