SCHEMBL3841503

SCHEMBL3841503

C#CCOc1ccc(C23CC4CC(C2)CC(C2C5CC6CC(C5)CC2(c2ccc(OCC#C)cc2OCC#C)C6)(C4)C3)c(OCC#C)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MDH2 P40926 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3844825 0.82 ADRA2A (0.33)
SCHEMBL3844863 0.82 GSTP1 (0.33) MDH2HIF1A
SCHEMBL3849520 0.82 KMT2A (0.34) MDH2HIF1A
SCHEMBL3840640 0.81 MEN1 (0.40) MDH2HIF1A
SCHEMBL3841823 0.79 KMT2A (0.32) MDH2HIF1A
SCHEMBL3849937 0.78 KMT2A (0.32) MDH2HIF1A
SCHEMBL3842360 0.77 MDH2 (0.33) MDH2HIF1A
SCHEMBL3846137 0.74 GSTP1 (0.34)
SCHEMBL3850515 0.72 GSTP1 (0.33)
SCHEMBL3841792 0.72 MAOB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed