Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.81 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.81 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.81 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22885190 | 1.00 | TAAR1 (0.81) | TAAR1SLC6A4SLC6A2SLC6A3PNMT | |
| SCHEMBL5673567 | 0.93 | TAAR1 (0.76) | TAAR1SLC6A4SLC6A2SLC6A3PNMT | |
| Tenamfetamine SCHEMBL30242630 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL15162053 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL30242515 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL9361151 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL29392330 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL393456 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL30904507 | 0.89 | TAAR1 (1.00) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Tenamfetamine SCHEMBL5305879 | 0.88 | TAAR1 (0.97) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118634-A2 | DRUG DETECTION KIT AND METHOD | Nathaniel, Andrew Homer (ZA) | 2009-11-18 | — | — | EP | claimed |
| US-20080254550-A1 | DRUG DETECTION KIT AND METHOD | NATHANIEL ANDREW HOMER | 2008-10-16 | — | — | US | claimed |
| WO-2008096225-A2 | DRUG DETECTION KIT AND METHOD | NATHANIEL ANDREW HOMER (ZA) | 2008-08-14 | — | — | WO | claimed |
| EP-2118634-A2 | DRUG DETECTION KIT AND METHOD | Nathaniel, Andrew Homer (ZA) | 2009-11-18 | — | — | EP | disclosed |
| US-20080254550-A1 | DRUG DETECTION KIT AND METHOD | NATHANIEL ANDREW HOMER | 2008-10-16 | — | — | US | disclosed |
| WO-2008096225-A2 | DRUG DETECTION KIT AND METHOD | NATHANIEL ANDREW HOMER (ZA) | 2008-08-14 | — | — | WO | disclosed |