Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | USP10 | Q14694 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | USP13 | Q92995 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1735749 | 0.99 | TP53 (0.39) | TP53USP10PIK3C3USP13KDM4E | |
| SCHEMBL27698493 | 0.91 | WNT3A (0.40) | TP53KDM4EHPGDALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1739201 | 0.89 | WNT3A (0.39) | TP53KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3842682 | 0.88 | LRRK2 (0.46) | TP53KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL3841998 | 0.88 | MAPT (0.44) | TP53USP10PIK3C3USP13KDM4E | |
| Hydrochloric Acid SCHEMBL1736673 | 0.87 | LRRK2 (0.45) | TP53KDM4EHPGDALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL1735367 | 0.87 | KMT2A (0.43) | KDM4EHPGDALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL1736917 | 0.87 | MAPT (0.43) | TP53USP10PIK3C3USP13KDM4E | |
| Hydrochloric Acid SCHEMBL1736652 | 0.87 | TP53 (0.41) | TP53USP10PIK3C3USP13KDM4E | |
| Hydrochloric Acid SCHEMBL1735357 | 0.85 | POLB (0.44) | TP53USP10PIK3C3USP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |