Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736673 | 0.99 | LRRK2 (0.45) | LRRK2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL27698493 | 0.91 | WNT3A (0.40) | POLBKDM4EALDH1A1HPGDLMNA | |
| Hydrochloric Acid SCHEMBL1739201 | 0.89 | WNT3A (0.39) | POLBKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL3841846 | 0.88 | TP53 (0.40) | KDM4EALDH1A1HPGDTP53EGFR | |
| SCHEMBL3844990 | 0.88 | LRRK2 (0.47) | LRRK2POLBKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1735749 | 0.87 | TP53 (0.39) | KDM4EALDH1A1HPGDTP53EGFR | |
| Hydrochloric Acid SCHEMBL1735367 | 0.87 | KMT2A (0.43) | KDM4EALDH1A1HPGDLMNACDK2 | |
| Hydrochloric Acid SCHEMBL1738514 | 0.87 | LRRK2 (0.46) | LRRK2POLBKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1737663 | 0.85 | POLB (0.47) | LRRK2POLBKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1736775 | 0.85 | LRRK2 (0.45) | LRRK2POLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |