Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636205 | 0.69 | DPP4 (0.39) | — | |
| SCHEMBL21358976 | 0.69 | DPP4 (0.39) | — | |
| SCHEMBL13647108 | 0.69 | — | — | |
| SCHEMBL27168395 | 0.69 | DPP4 (0.39) | — | |
| SCHEMBL23716523 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL20873513 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL20873514 | 0.69 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL5178203 | 0.67 | BRD4 (0.38) | — | |
| SCHEMBL4684582 | 0.67 | — | — | |
| SCHEMBL15817157 | 0.67 | HPGD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362845-B1 | New process for the synthesis of N-((S)-1-carboxybutyl)-(S)-alanine esters and their use in the synthesis of perindopril | SERVIER LAB (FR) | 2009-10-14 | — | — | EP | disclosed |
| US-7361757-B2 | Method for synthesizing esters of N-[(S)-1-carboxybutyl]-(S)-alanine and use thereof for synthesizing perindopril | LES LABORATOIRES SERVIER (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060252958-A1 | Novel method for synthesizing esters of n-[(s)-1-carboxybutyl]-(s)-alanine and use thereof for synthesizing perindopril | LES LABORATOIRES SERVIER (FR) | 2006-11-09 | — | — | US | disclosed |
| EP-1362845-A2 | New process for the synthesis of N-((S)-1-carboxybutyl)-(S)-alanine esters and their use in the synthesis of perindopril | Les Laboratoires Servier (FR) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252958-A1 | Novel method for synthesizing esters of n-[(s)-1-carboxybutyl]-(s)-alanine and use thereof for synthesizing perindopril | ACE, AGT, AGTR1 | NAAA 447/4885HTT 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.