SCHEMBL384205

SCHEMBL384205

C=CCc1ccccc1[O]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.47
GABRB2 P47870 2/20 0.47
ADRA2C P18825 4/20 0.38
ADRA2B P18089 3/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.37
POLB P06746 1/20 0.36
AKR1B1 P15121 1/20 0.36
ADRA2A P08913 2/20 0.36
HTR1A P08908 2/20 0.35
NISCH Q9Y2I1 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
ADRB3 P13945 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763626 0.82 GABRA1 (0.56) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL173300 0.82 GABRA1 (0.56) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL968136 0.80 GABRA1 (0.47) GABRA1GABRB2ADRA2CADRA2BALDH1A1
Phosphine SCHEMBL28908229 0.79 GABRA1 (0.54) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL11765775 0.79 GABRA1 (0.54) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL19437729 0.79 GABRA1 (0.54) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL10528834 0.79 GABRA1 (0.54) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL4000170 0.78 GABRA1 (0.42) GABRA1GABRB2ADRA2CADRA2BALDH1A1
SCHEMBL11879176 0.78 ICAM1 (0.44) ADRA2CADRA2BALDH1A1KDM4EADRA2A
SCHEMBL4456728 0.78 GABRA1 (0.54) GABRA1GABRB2ALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4979 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085586-A Flame-retardant polyphosphazene foam material and preparation method thereof 北京化工大学 2024-05-28 CN claimed
CN-113508156-B Quick moisture curable polyethylene formulations 陶氏环球技术有限责任公司 2024-05-03 CN claimed
CN-117924281-A Reversible light response compound, preparation method and application thereof, self-assembly system, graphene composition and photoelectric functional device 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-114230793-B Modified bismaleimide prepolymer and preparation method and application thereof 苏州生益科技有限公司 2024-03-29 CN claimed
CN-115819317-B Active ester compound and resin composition 苏州生益科技有限公司 2024-03-08 CN claimed
CN-117497853-A Nonaqueous electrolyte additive, nonaqueous electrolyte and secondary battery 蓝固(湖州)新能源科技有限公司 2024-02-02 CN claimed
CN-115820166-B Adhesive for bonding polyphosphazene rubber and metal, preparation method and application 西安近代化学研究所 2023-12-12 CN claimed
US-20230383063-A1 CROSSLINKED POLYPHOSPHAZENE BLENDS FOR GAS SEPARATION MEMBRANES US ENERGY (US) 2023-11-30 US claimed
CN-116675650-B Lithium ion battery electrolyte additive, lithium ion battery electrolyte and lithium ion battery 蓝固(淄博)新能源科技有限公司 2023-10-31 CN claimed
CN-116675650-A Lithium ion battery electrolyte additive, lithium ion battery electrolyte and lithium ion battery 蓝固(淄博)新能源科技有限公司 2023-09-01 CN claimed
US-4051103-A Stabilization of polyfluorophosphazenes with zinc hippurate THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-09-27 US claimed
US-4011045-A TURBIDITY REDUCTION IN TRIGLYCERIDE STANDARDS BONDERMAN DEAN P 1977-03-08 US claimed
US-4008202-A Aqueous thickening agents derived from vinyl benzyl ether polymers THE DOW CHEMICAL COMPANY (US) 1977-02-15 US claimed
US-4003998-A CARDIOTONICS BOEHRINGER INGELHEIM GMBH (DT) 1977-01-18 US claimed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US claimed
US-3991130-A Organo-nickel salts as adhesion promotors for vulcanizable elastomers to metals CIBA-GEIGY CORPORATION (US) 1976-11-09 US claimed
US-3989643-A FATTY ACID ZINC SALT IN AN ALKYLPHENOXY POLYGLYCOL TECHNICAL PROCESSING, INC. (US) 1976-11-02 US claimed
US-3970533-A PHOSPHONITRILE FLUOROELASTOMER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-07-20 US claimed
US-3968150-A Process for the preparation of nitrogen- and fluorine-containing acrylates and methacrylates ROHM AND HAAS COMPANY (US) 1976-07-06 US claimed
US-3950395-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US claimed