Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802708 | 0.95 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL1809913 | 0.95 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL13813722 | 0.95 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL3837074 | 0.85 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL3837001 | 0.85 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL5108976 | 0.84 | P2RX7 (0.61) | P2RX7 | |
| Trifluoroacetic Acid SCHEMBL3836980 | 0.82 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL3843656 | 0.80 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL1804368 | 0.79 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL5745880 | 0.78 | P2RX7 (0.67) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633717-B1 | P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | ASTRAZENECA AB (SE) | 2009-10-28 | — | — | EP | claimed |