Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3840039 | 0.94 | TSHR (0.30) | TSHR | |
| Hydrochloric Acid SCHEMBL17491836 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL17491834 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL10385741 | 0.74 | TSHR (0.36) | TSHR | |
| Hydrochloric Acid SCHEMBL28895 | 0.74 | — | — | |
| SCHEMBL6279321 | 0.74 | TSHR (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL6239479 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL17491849 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6249490 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL1451332 | 0.70 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936672-B2 | Mold addition polymerization of norbornene-type monomers using group 10 metal complexes | SUMITOMO BAKELITE CO., LTD. (JP) | 2005-08-30 | — | — | US | claimed |
| EP-1155057-B1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | SUMITOMO BAKELITE CO (JP) | 2005-06-22 | — | — | EP | claimed |
| US-20030120006-A1 | In mold addition polymerization of norbornene-type monomers using group 10 metal complexes | THE B.F. GOODRICH COMPANY | 2003-06-26 | — | — | US | claimed |
| US-6350832-B1 | CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION | THE B. F. GOODRICH COMPANY | 2002-02-26 | — | — | US | claimed |
| EP-1155057-A1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | The B.F.Goodrich Co. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000034344-A1 | IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES | THE B.F.GOODRICH COMPANY (US) | 2000-06-15 | — | — | WO | claimed |
| US-10245562-B2 | Pervaporation membranes derived from polycyclo-olefinic block copolymers | PROMERUS, LLC (US) | 2019-04-02 | — | — | US | disclosed |
| US-10174171-B2 | Nanoporous films derived from polycyclo-olefinic block polymers | PROMERUS, LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-9771443-B2 | Chain transfer agent for addition mass polymerization of polycycloolefinic monomers | PROMERUS, LLC (US) | 2017-09-26 | — | — | US | disclosed |
| US-9610549-B2 | Polycyclo-olefinic block copolymers | PROMERUS, LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20170015790-A1 | NANOPOROUS FILMS DERIVED FROM POLYCYCLO-OLEFINIC BLOCK POLYMERS | PROMERUS, LLC (US) | 2017-01-19 | — | — | US | disclosed |
| US-20160289353-A1 | CHAIN TRANSFER AGENT FOR ADDITION MASS POLYMERIZATION OF POLYCYCLOOLEFINIC MONOMERS | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-10-06 | — | — | US | disclosed |
| US-9415354-B2 | Organopalladium compounds as polymerization catalysts | PROMERUS, LLC (US) | 2016-08-16 | — | — | US | disclosed |
| US-20160046752-A1 | POLYCYCLO-OLEFINIC BLOCK COPOLYMERS | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| US-20160046657-A1 | ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| US-8445630-B2 | Polymers | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| EP-1858976-B1 | NOVEL POLYMERS | BASF SE (DE) | 2009-10-14 | — | — | EP | disclosed |
| US-20090105447-A1 | Novel Polymers | UDC IRELAND LIMITED (IE) | 2009-04-23 | — | — | US | disclosed |
| EP-1858976-A1 | NOVEL POLYMERS | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006097419-A1 | NOVEL POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105447-A1 | Novel Polymers | PLEC, VIM, PUF60 | TSHR 4829/4885 |
| US-20160046657-A1 | ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS | MVD, DDT, CDV3 | TSHR 4854/4885 |
| US-10245562-B2 | Pervaporation membranes derived from polycyclo-olefinic block copolymers | VAPB, NOTUM, VAPA | TSHR 4861/4885 |
| US-20170015790-A1 | NANOPOROUS FILMS DERIVED FROM POLYCYCLO-OLEFINIC BLOCK POLYMERS | VAPB, VAPA, OR10J3 | TSHR 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.