Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL499589 | 0.98 | SMN1; SMN2 (0.41) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL15901633 | 0.89 | TNNC1 (0.39) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL27690429 | 0.81 | TAAR1 (0.50) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL15901709 | 0.80 | TAAR1 (0.45) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL25288830 | 0.79 | TNNC1 (0.47) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL6947634 | 0.79 | TNNC1 (0.47) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| Bromide SCHEMBL11785245 | 0.79 | MAOA (0.48) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL9768679 | 0.78 | HTR2A (0.52) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| Hydrochloric Acid SCHEMBL17710417 | 0.78 | S1PR1 (0.49) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 | |
| SCHEMBL10766520 | 0.77 | TAAR1 (0.45) | SMN1; SMN2TAAR1HTR2ACYP2A6LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848336-B1 | METHOD FOR MANUFACTURING HOLLOW METAL NANOPARTICLES | LG CHEMICAL LTD (KR) | 2017-04-26 | — | — | EP | claimed |
| EP-1898882-B1 | NANOPARTICULATE EBASTINE FORMULATIONS | ELAN PHARMA INT LTD (IE) | 2009-10-28 | — | — | EP | claimed |