Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.52 |
| ▸ | PPARG | P37231 | 11/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842820 | 0.96 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL3841453 | 0.96 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3286740 | 0.96 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3843706 | 0.93 | PPARA (0.44) | PPARAPPARGPPARDKCNH2PCSK9 | |
| SCHEMBL3288383 | 0.92 | PPARA (0.53) | PPARAPPARGPPARDKCNH2PCSK9 | |
| SCHEMBL3849871 | 0.92 | PPARA (0.48) | PPARAPPARGPPARDPCSK9 | |
| SCHEMBL3845816 | 0.92 | PPARA (0.47) | PPARAPPARGPPARDPCSK9 | |
| SCHEMBL3849260 | 0.91 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3840604 | 0.91 | PPARA (0.47) | PPARAPPARGPPARDPCSK9 | |
| SCHEMBL3841451 | 0.91 | PPARA (0.58) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |